Sertraline Hydrochloride, USP

Sertraline Hydrochloride, USP

CAS: 79559-97-0

 

Sertraline Hydrochloride, USP is a white to off-white, odorless crystalline powder. It is sparingly soluble or slightly soluble in absolute alcohol, while slightly soluble in water and in isopropanol.

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1. Which vehicle is commonly used to compound sertraline hydrochloride oral liquid?
 
Based on practical experience, glycerin is the ideal vehicle choice for an oral liquid with sertraline hydrochloride.
 
 
2. Which CapsuBlend™  is recommended to compound sertraline hydrochloride oral capsules?
 
CapsuBlend™-S is recommended when compounding sertraline hydrochloride in oral capsules.
 
Kasim NA, Whitehouse M, Ramachandran C, Bermejo M, Lennernäs H, Hussain AS, Junginger HE, Stavchansky SA, Midha KK, Shah VP, Amidon GL. Molecular properties of WHO essential drugs and provisional biopharmaceutical classification. Mol Pharm. 2004 Jan 12;1(1):85-96.